Human Growth hormone deficiency happens when your pituitary gland does not make enough growth hormone (HGH). This is usually caused by a tumor pressing on the pituitary gland. The pressure can damage the gland and keep it from making enough GH, Slow growth may first be noticed in infancy and continue through childhood. Deficiency of growth hormone (HGH) in adults results in a syndrome characterized by decreased muscle mass and exercise capacity, increased visceral fat, impaired quality of life, unfavorable alterations in lipid profile and markers of cardiovascular risk, decrease in bone mass and integrity, and increased mortality.
Human Growth hormone deficiency (GHD) is a disorder that may affect both children and adults. The underlying cause is insufficient growth hormone (HGH) production by the pituitary gland, which results in slower than normal growth for children. Human Growth hormone deficiency may also affect adults and result in a variety of symptoms including reduced muscle and bone strength, larger waist size, reduced muscle and increased fat in body composition, and high cholesterol. It can even result in psychological symptoms such as depression, tiredness, and lack of motivation.
The pediatrician will usually draw the child's growth curve on a growth chart. Children with growth hormone deficiency have a slow or flat rate of growth. The slow growth may not show up until a child is 2 or 3 years old. The child will be much shorter than most children of the same age and gender. The child will still have normal body proportions, but may be chubby. The child's face often looks younger than other children of the same age. The child will usually have normal intelligence.
Often the failure symptoms (clinical symptoms) when the growth hormone is lowered is not distinguished from those of a testosterone deficiency. Growth hormone (HGH) as the name implies, is responsible for the growth of the organs and tissues during childhood and puberty, which is why the blood levels of growth hormone around puberty reach the highest values, then fall sharply.
Growth hormone is formed in the pituitary gland and thrown into the bloodstream. It enters the liver. There, growth hormone causes the insulin like growth factor 1 (IGF-1) to be formed, which is the actually responsible substance for the biological effects of growth hormone.
Human Growth hormone (HGH) in particular positively influences the protein synthesis and thus also the muscle composition and the muscle mass. For this reason, growth hormone has been used in the past as a doping agent in the performance pool. Growth hormone increases fat mobilization by hydrolysis of the triglycerides, resulting in a redistribution of the body fat, thereby reducing the waist / hip ratio.